izindaba

I-Collagen Peptides

UCollagen uyiprotheni ebalulekile edlala indima ebalulekile ekugcineni lesakhiwo, amandla, kanye nokuqina kwezicubu ezahlukahlukene emzimbeni womuntu. Njengoba amaprotheni amaningi kakhulu ezincelisayo, ama-collagen abiza ama-30% esisindo seprotheni ephelele. Eminyakeni edlule, ama-collagen ama-peptides - abizwa nangokuthi i-hydrolyzed collagen noma i-collagen hydrolyzate - ithole ukunakwa okubalulekile ngezinzuzo zazo ezingaba khona zezempilo nezinhlelo zokusebenza ezivelayo ezibanzi. Kulesi sihloko, sihlola ama-portides a-collagen, imithombo yawo, ama-bioavailability, kanye nezindlela ezahlukahlukene abangazithinta kahle impilo yabantu.

Yini ama-collagen ama-peptides?

Ama-pollagen ama-peptides asuselwa ku-collagen ngokusebenzisa inqubo eyaziwa ngokuthi yi-enzymatic hydrolysis. Le nqubo ibhidliza ama-molecule amakhulu ahlanganisiwe abe ngama-peptides amancane, abenze bathengeke ngokwengeziwe futhi badonswe kalula ngumzimba. Ama-peptides avelayo ngokuvamile aqukethe ukuxubana kwama-amino acid, kufaka phakathi i-glycine, i-proline, kanye ne-hydroxyproline, okubalulekile ukuze kugcinwe impilo yezicubu ezihlangene.

Imithombo yama-collagen ama-peptides

Ama-portiden e-collagen angatholakala emithonjeni ehlukahlukene, zombili izilwane nezasolwandle. Imithombo esetshenziswa kakhulu ifaka phakathi:
I-Bovine (Izinkomo):Yaziwa ngokuqukethwe kwayo okuphezulu kwe-collagen, ikakhulukazi emathanjeni nesikhumba.
I-PORCINE (izingulube):Inikeza iphrofayili efanayo efanayo ye-Amino Acid ku-Bovine Collagen, evame ukusetshenziswa ngezithasiselo.
Inyama yenkukhu:Ucebile ngohlobo II Collagen, uzuzisa ikakhulukazi impilo ehlanganyelwe.
Izinhlanzi (Marine Collagen):Kuthathwe esikhunjeni sezinhlanzi, esikalini, noma amathambo, futhi kuvame ukubhekwa njengokuphakeme ngenxa ye-bioavailability yayo ephezulu kanye nesisindo esiphansi samangqamuzana.

Umthombo ngamunye unikeza iphrofayili ehlukile ye-Amino Acid, kepha bonke bahlinzeka izakhi ezibalulekile zokwenza ngcono ukuqina kwesikhumba, umsebenzi ohlanganyelwe, kanye nempilo yonke.

I-Bioavailability kanye nokutholwa

I-Hydrolyzed Collagen Peptudes ine-bioavailobility ethuthukisiwe kakhulu ngenxa yesisindo sayo esiphansi, esivumela ukugaya ngokushesha kanye nokumunca epheshana lesisu. Ngenxa yalokhu, ama-amino acid alethwa kahle ekuhloselweni kwezicubu ezifana nesikhumba, amalunga, amathambo nezinye izicubu ezixhunyiwe. Ucwaningo luye lwabonisa ukuthi ama-collagen ama-peptides athathwa kalula futhi asatshalaliswa kuwo wonke umzimba, enikeza izinzuzo ezithile kohlobo oluthile lwezicubu.

 

Izinzuzo zezempilo ze-collagen peptides

Impilo yesikhumba

Ama-polliden ama-peptides aboniswe ukuthuthukisa impilo yesikhumba ngokuthuthukisa i-hydration, ukuqina, kanye nokuqina, ngenkathi futhi enciphisa ukubukeka kwemibimbi nemigqa emihle. Ucwaningo lukhombisa ukuthi ukungenisa okungeziwe kwe-collagen kungakhulisa ukukhiqizwa kwe-collagen esikhunjeni, kusize ukubuyisela ukubukeka kwayo kobusha futhi kukhuthaze amandla wesikhumba jikelele. Isibonelo, asserin et al. (2015) uthole imiphumela emihle kumswakama wesikhumba kanye nokwakheka kwenethiwekhi ye-collagen.

Impilo ehlanganisiwe nethambo

I-Collagen Peptudes isekela impilo ehlanganayo ngokuvuselela ukukhiqizwa kwe-collagen kanye namaprotheni ku-cartilage, okungasiza ukunciphisa izinhlungu futhi kuthuthukise ukuhamba kubantu abathile nge-osteoarthritis. Ngokwengeziwe, ama-pollagen ama-peptides anikela ngempilo yethambo ngokuvuselela ama-osteoblasts (amaseli abhekele ukwakheka kwamathambo), okuholela emathanjeni anamandla kanye nengozi encishisiwe yokuqhekeka. Ucwaningo nguBello no-Oesser (2006) noClark et al. (2008) bakhombise izinzuzo ezibalulekile zokungezwa kwe-collagen ngempilo ehlanganisiwe nethambo.

Ukusebenza kwezemidlalo kanye nokubuyiselwa kwemisipha

I-Collagen Peptides icebile kuma-amino acid athile, njenge-glycine ne-proline, edlala indima ebalulekile ekubuyeni kwemisipha nokukhula. Ukungezelela ama-collagen ama-peptides kungasiza ekubuyiselweni kwemisipha, ukunciphisa izinhlungu ezihlangene zokuzivocavoca, futhi kuthuthukise ukusebenza kwezemidlalo, kubenza babe ukukhetha okuthandwayo phakathi kwabadlali abasubathi kanye nokuqina komzimba. Isifundo se-Guillerminet et al. (2012) kwabonisa imiphumela emihle yokungezwa kwe-collagen nge-metabolism yamathambo, engazuzisa abasubathi.

Impilo ye-gust

I-Collagen Peptides, ikakhulukazi i-amino acid glycine, isekela impilo ye-gut ngokuqinisa i-lining yamathumbu futhi ithuthukise ukugaya okufanele. Baxhumene nokwenza ngcono izimo ezifana ne-Leaky Tut Syndrome futhi zingase zikhulise umsebenzi wokugaya ukudla, zisiza ukugcina i-microbiome enempilo.

Izicelo ezingaphezulu kwempilo

I-Collagen Peptides isetshenziswa ezimbonini ezahlukahlukene, kufaka phakathi ukudla neziphuzo, izimonyo kanye nemithi. Bafakwa ekudleni okucebile ngamaprotheni, izithasiselo zokudla, kanye nemikhiqizo yobuhle ngenxa yokuhlanganiswa kwayo okulula, izinzuzo ezisebenzayo, kanye nokusebenza ngokuhlukahlukene. Ama-Polliden Peptides nawo ahlolisiswa ngenxa yamandla abo ekwenziweni kwemithi okuhloswe ngayo ukusekela impilo ehlanganayo, ukuguga kwesikhumba kanye nokubuyiselwa kwemisipha.

Ukugcina

I-Collagen Peptudes ivele njengesengezo esinamandla sokudla okunezinzuzo eziningi zezempilo. Ukusuka ekuthuthukiseni impilo yesikhumba kanye nomsebenzi ohlanganyelwe ukusekela ukululama kwemisipha kanye nokwenza ngcono impilo ye-gut, ama-pollagen ama-peptides anikela ngezicelo ezahlukahlukene zokwenza ngcono inhlala-kahle. I-Bioavailability yazo ephezulu, ukwakheka okuqondile kwe-Amino Acid, kanye nezinketho eziningi zokuthola ama-sourcing zibenza babe isithako esiguquguqukayo ngezinhloso ezahlukahlukene ezihlobene nezempilo. Njengoba ucwaningo oluqhubekayo luqhubeka ukwembula izinzuzo ezintsha, ama-pollagen ama-ceptides abamba amandla amakhulu ekwenzeni ngcono impilo yabantu kanye nekhwalithi yempilo.

 

Ukunqubekela phambili

• Assurin, J., Lati, E., E. Shioya, T., & Prawitt, J. (2015).Umphumela we-Oral Collagen Peptide Supplementation on Skin umswakama kanye nenethiwekhi ye-dermal collagen.Ijenali ye-cosmetic dermatology, 14 (4), 291-301.https://doi.org/10.1111/jocd.12199
• UBello, ae, no-Oesser, S. (2006).I-Collagen hydrolyzate yokwelashwa kwama-osteoarthritis kanye nezinye izinkinga ezihlangene.Ucwaningo lwamanje lwezokwelapha kanye nemibono, 22 (11), 2221- 2232.https://doi.org/10.1185/030079906x149114
• Clark, KL, Sebastiayelli, W., Flechsenhar, KR, Aukermann, DF, Meza, F., Millard, RL (2008).Ucwaningo lwamasonto angama-24 ukusetshenziswa kwe-Collagen hydrolyzate njengesengezo sokudla kubasubathi abanobuhlungu obuhlangene obuhlobene nomsebenzi.Ucwaningo lwamanje lwezokwelapha kanye nemibono, 24 (5), 1485-1496.https://doi.org/10.1185/030079905x289385
• I-Guillerminet, F., Fabien-Soulé, V., Noma, PC, & & Tomé, D. (2012).I-Hydrolyzed Collagen ithuthukisa amathambo metabolism namapharamitha e-biomechanical kumagundane e-ovariectomised: an vitro nasezifundweni ze-vivo.Ithambo, 50 (3), 876-883.https://doi.org/10.1016/J.bone.3111.032
• I-Volmer, DL, entshonalanga, VA, neLephart, ed (2018).Ukuthuthukisa Impilo Yesikhumba: Ngokuphathwa komlomo kwezimpawu zemvelo kanye namaminerali anemiphumela kwi-Dermal Microbiome.I-International Journal of Molecular Science, 19 (10), 3059.https://doi.org/10.3390/IJMS19103059